Feline panleukopenia virus (FPV, also known as feline parvovirus) and feline coronavirus (FCoV) are contagious pathogens responsible for acute gastroenteritis in cats. Despite structural, genetic, molecular biological, and pathological differences, initial clinical signs of two viruses, including diarrhea, vomiting, fever, lethargy, and anorexia, are very similar when infected with cats.